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Thinking Like a Phage: The Genius of the Viruses That Infect Bacteria and Archaea, by Merry Youle
Free Download Thinking Like a Phage: The Genius of the Viruses That Infect Bacteria and Archaea, by Merry Youle
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Review
It took about 100 years of phage research for us to realize that phages (and viruses in general) dominate cellular life, there being 10 to 100 times more phages than hosts. Wherever hosts live, phages seem to be there, too. Phages were also front and center when the field of molecular biology emerged. These messages should be distributed to the entire biology-oriented public in an easily readable way. Youle's phage book certainly offers this opportunity. Very good for new comers and those who do not remember anymore. --- Dennis Bamford, Professor Emeritus, University of Helsinki Thinking Like a Phage is an engaging book that has the reader imagining what it is like to be a bacteriophage and to encounter the various challenges it faces, be it an obstinate cell wall, CRISPR fortifications, or a multitude of eager phage competitors. The range of depth and breadth of Thinking Like a Phage will delight every reader from the phage aphicianado to the student eager for immersion in the phascinating world of bacteriophages. --- Graham F. Hatfull, HHMI Professor, University of Pittsburgh Whether you are an advanced high school or college student, a general science enthusiast, or a an established researcher or biology teacher seeking stimulating ways to introduce concepts in the classroom, “Thinking Like a Phage” is enjoyable and informative reading. The author, Merry Youle, astutely chooses specific phages to illustrate key life-cycles stages, viral-host interactions, and evolutionary concepts. The writing is witty and engaging, yet technically accurate and thorough. Together, the original artwork and the enthusiastic prose produce an unusually refreshing scientific narrative. --- Bentley Fane, Professor, University of Arizona The phage phield has a nasty little secret: there is not a good introductory book for students and others interested in the most abundant life forms on the planet. Merry Youle has fixed this in the extraordinarily well-written Thinking Like a Phage. Concise, well-balanced in topics and current with the latest research, TLAP is a delight to read for the novice and expert alike. The incredible illustrations by Leah Pantea are both informative and beautiful. TLAP is the overview that the phage phield needs and a phascinating journey through the world's most interesting biology. --- Forest Rohwer, Professor, San Diego State University My students will enjoy reading scientific information that is presented in such a clear, interesting and exciting manner. Chapter 1 is the best introduction to bacteriophage biology I have seen yet – hits all of my favorite topics! The book spotlights many of the usual suspect phage that we don’t talk a lot about but that I want my students to know exist, as well as some of the truly weirdo phage. --- Sally Molloy, Assistant Professor, University of Maine Our world is populated by untold numbers of creatures, but none are more abundant than the viruses that infect bacteria: the phages. This unseen realm plays a huge role in every ecosystem, yet its very existence is nearly universally unnoticed. It badly needs an advocate, and none serve better than Merry Youle. In these pages, she portrays this domain with aptly chosen examples, each described in an inviting, sometimes even witty, narrative. Be prepared to enter a splendid garden and view Nature at its most ingenious. --- Moselio "Elio" Schaechter, Distinguished Professor Emeritus, Tufts University School of Medicine
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About the Author
Merry Youle is coauthor of two previous books - Life in Our Phage World and Coral Reefs in the Microbial Seas - andof more than a dozen research papers. She also contributed over 40phage-related posts to Elio Schaechter's ASM-sponsored blog, Small Things Considered. She plans tocontinue writing about her beloved phages from her home on the Big Island.
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Product details
Paperback: 310 pages
Publisher: Wholon; abridged edition edition (May 1, 2017)
Language: English
ISBN-10: 0990494314
ISBN-13: 978-0990494317
Product Dimensions:
6 x 0.8 x 9 inches
Shipping Weight: 1 pounds (View shipping rates and policies)
Average Customer Review:
4.8 out of 5 stars
12 customer reviews
Amazon Best Sellers Rank:
#732,057 in Books (See Top 100 in Books)
Great for anybody interested in microbiology, viruses, life, science, how the world really works, and/or having their mind frequently blown.It's extremely approachable and full of little moments of genius and you won't come out of it looking at the world the same way.
In this book Merry Youle provides a beautifully drawn and articulated introduction into the amazing world of bacteriophages. The book remains accessible enough to be of interest to the curious undergrad or general audience, while also elegantly explaining intricate details of bacteriophages in a way that will educate even the most seasoned phage veteran. One example of this is how Youle has renamed the phages within her book, taking inaccessible jargon, such as øFf49, and transforming it into the descriptive and memorably named 'Skinny' phage based on its thin, filament-like structure.
This is a fantastic book full of exciting ideas. If you love learning about the amazing tricks of nature you HAVE to get this book! P.S. It is a much more scholarly and rigorous book than the anthropomorphic title implies.
Technical but easily understood by a layman
I'm not a biologist, but I found this book to be strangely intriguing nevertheless. It delves into life at the micro level more interesting to me than most works of science fiction. The phage, it seems, is a remarkable bit of life that may or may not actually be alive, depending on how one defines the concept of life. The aspect of the book that was most engrossing was the way in which these creatures invade larger host organisms, and then, like the key to some cosmic lock, turn the host's DNA towards their own purposes. The first of these purposes is, of course, self-replication, but that's just the start of the strange odyssey of the phage.If the invasion of a living host organism seems macabre, it must be said also that these entities are responsible for much of the genetic innovation underpinning the evolving process of life. So these infinitely small, and incomprehensibly multitudinous creatures, both destroy life and bring forth new life in the process. So if I understand the thrust of this book correctly, admittedly a stretch for a layman such as myself, it seems the phage is a sort of cross between a magician and an engineer, recreating and redefining life towards it's own elaborate and mysterious ends. The process it uses to accomplish this task is what the book is about and it is indeed the stuff of real life science fiction.
Merry Youle, the Phage Whisperer, is back with another nuanced, insightful, and profound work.This book is both detailed enough for the serious student of viruses and broad enough to engage any newcomer. The glue that binds this book together is the author's deep sense of wonder at the workings of the world that rings through in every sentence, and specifically how viruses - the master manipulators of life - get business done. The author's passion for the subject matter is tangible and refreshing and filled me with a sense of newfound excitement to explore the world more.A real gem.
"Thinking Like a Phage" does what many books on the microbial world fail to do: consider the life cycle of bacteriophages from their perspective rather than that of the humans who study them. Merry Youle's sense of wonder gives each phage a personality that lets her human audience connect with them without overly anthropomorphizing the viruses. Complemented by Leah Pantea's watercolor illustrations and Ben Darby's pen and ink portraits, the textual descriptions of phages and their world of stalking, infecting, and exploiting their prey comes alive. Youle does assume her audience has a small background in basic molecular biology; however, her humor and conversational tone makes this book accessible to those who aren't scientists in the phage field.
I like it. In the spirit of the HHMI SEA-PHAGES educational program, the author has conveyed life-style appropriate names to classic, well-studied phages and to those more recently discovered with intriguing structures, niches or hosts. If you desire a more a more technical monograph on phage biology, seek R. Calendar's "The Bacteriophages". But if you'd like to introduce first year biology students or students and readers of any discipline, this is good place to start. The book covers the molecular biology of several phage types wiithout being over technical. Representative but not exhaustive(ing) references are provided and there is a comprehensive glossary sufficient to carry any new phage explorer into the field. I would recommend it to first year and wizened students of microbiology, molecular biology and bacteriophages everywhere.Leah Pantea's illustrations of ink and watercolor are a fabulous accompaniment. Whether intended or not, the colorful flow of watery blues with earthly browns among the cells and phage imbue the figures with the impression of phage throughout the planet..... which they are! And with the watercolors----- I see a T-shirt and coffee mug industry in the making!
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